A new and more powerfully activating diamine for practical and scalable enantioselective aldehyde crotylsilylation reactions.
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چکیده
منابع مشابه
Picolylamine as an organocatalyst template for highly diastereo- and enantioselective aqueous aldol reactions.
A pyridine based 1,2-diamine containing only one stereogenic center has been identified for fast aldol reactions (16-48 h). Using 2-5 mol% of (R)- or (S)-PicAm-2, cyclohexanone (3.3 equiv) readily undergoes aldol reactions with o-, m-, and p-substituted aromatic aldehyde partners (limiting reagent), including the poor electrophile 4-methylbenzaldehyde (95-99% ee). Furthermore, functionalized cy...
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The development of a new transition-metal-catalyzed transformation can often allow a traditional reaction, perhaps one that employs stoichiometric amounts of reagents and harsh reaction conditions, to be replaced by a selective, atom economic process which proceeds under mild reaction conditions. This is certainly the case with the recent report from Dong and co-workers of a catalytic enantiose...
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An efficient tandem synthesis of alkyl aryl ethers, including valuable building blocks of dialdehyde and dinitro groups under microwave irradiation and solvent free conditions on potassium carbonate as a mild solid base has been developed. A series of alkyl aryl ethers were obtained from alcohols in excellent yields by following the Williamson ether synthesis protocol under practical mild condi...
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عنوان ژورنال:
- Chemical science
دوره 4 6 شماره
صفحات -
تاریخ انتشار 2013